US 2024/0352076 A1 · SPECIFIC BACULOVIRUS MAJOR ENVELOPE GLYCOPROTEIN GP64 BINDING PROTEINS

Abstract

gp64 is the major envelope glycoprotein of baculoviruses. The present invention relates to novel proteins that specifically bind to the baculovirus envelope protein gp64. The novel proteins of the present invention are advanced and powerful tools because they allow precise capturing of gp64 in affinity chromatography. The gp64 binding proteins are particularly useful tools within the process of protein production (e.g. vaccine production) to provide for gp64 free samples. Further, the binding protein for gp64 are useful for methods to analyze the presence of gp64.

Claims15

Dependent claims

A baculoviral envelope protein gp64 binding protein comprising an amino acid sequence with at least 90% sequence identity to SEQ ID NO:

1, SEQ ID NO:
2, or SEQ ID NO:
3, wherein the baculoviral envelope protein qp64 binding protein has a binding affinity of less than 100 nM for gp64.

Dependencies are inferred from the claim text.

Facts

Application

18/629,324Filed 7 Oct 2022

Priority

EP 21201661.28 Oct 2021

Published

24 Oct 2024

Term ends

Not estimatedThe source records don’t support an estimate.

Classification13 codes

C07K 14/005
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof: from viruses
C07K 14/31
From Micrococcaceae: from Staphylococcus
C07K 1/22
By chromatography: affinity chromatography or related techniques based upon selective absorption processes
C07K 14/245
From Enterobacteriaceae , e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia: escherichia

Specific baculovirus major envelope glycoprotein gp64 binding proteins

Life of this patent

Specific baculovirus major envelope glycoprotein gp64 binding proteins

Life of this patent

Abstract

Claims15