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US 2024/0352066 A1Published application
Antimicrobial compounds and the method of use
AssigneeMiddle Tennessee State University
InventorsKevin Lee Bicker, Robert Madison Green
Life of this patent
Estimating the term…
Abstract
Antimicrobial peptoids, compositions thereof, and methods of use. Antimicrobial peptoids or compositions thereof may be used to treat or prevent a fungal infection in a vertebrate. Antimicrobial peptoids or compositions thereof may be used to treat or prevent a fungal infection in a plant.
Claims30
A compound of the general formula,
- wherein:
- AX is H or a linear or branched (C6-C20)alkyl or a linear or branched (C6-C20)alkenyl, wherein the alkyl or the alkenyl optionally includes a carbonyl group;
- T is a linear or branched (C6-C20)alkyl or a linear or branched (C6-C20)alkenyl, wherein the alkyl or the alkenyl optionally includes a carbonyl group;
- Q is a hydroxyl or NH2;
- and
- R1, R2, R3, and R4 are each independently
- or an alkyl amine of the general formula R10NR11R12R13,
- wherein:
- for each R1, R2, R3, and/or R4, each n is 0, 1, or 2;
- for each R1, R2, R3, and/or R4 that is NcpenW, each W is independently N, S, or O;
- for each R1, R2, R3, and/or R4 that is NlinW, each W is independently N, S, or O;
- for each R1, R2, R3, and/or R4 that is NphX, each X is independently F, Cl, Br, or I;
- for each R1, R2, R3, and/or R4 that is NapenZ, each Z is independently S, or O;
- for each R1, R2, R3, and/or R4 that is R10NR11R12R13, R10 is a linear (C1-C6)alkylene;
- and
- for each R1, R2, R3, and/or R4 that is R10NR11R12R13, R11, R12, and R13 are each independently H or (C1-C6)alkyl.
13 more elements
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30-33. (canceled)
Dependencies are inferred from the claim text.