Back to results
US 2024/0347239 A1Published application
Core-Shell Nanodisc Synthesis and Applications to Single-Particle Targeted Magnetothermal Control of Biological Signaling
AssigneeMassachusetts Institute of Technology
InventorsPolina Olegovna ANIKEEVA, Ye Ji Kim, Florian Koehler
Life of this patent
Estimating the term…
Abstract
Anisotropic magnetothermal nanoparticles and methods for making the same are disclosed. The anisotropic magnetothermal nanoparticle may include a core and a shell. The core may include hexagonal nanodisc hematite (Fe2O3). The shell may include AxFe3-xO4, where A=Co, Mn, Ni, Fe, Zn, Mg, or Cu. The anisotropic magnetothermal nanoparticle may also include a polymer coating.
Claims20
A method of making an anisotropic magnetothermal nanoparticle, the method comprising:
- forming a magnetite nanodisc via reduction of hexagonal nanodisc hematite;
- and
- growing AxFe3-xO4 on the magnetite nanodisc to form the anisotropic magnetothermal nanoparticle, where A is one of Co, Mn, Ni, Fe, Zn, Mg, or Cu.
An anisotropic magnetothermal nanoparticle comprising:
- a magnetite core having a maximum lateral dimension of about 170 nm to about 550 nm, a minimum thickness of at least about 20 nm, and a maximum thickness of up to 50 nm;
- and
- an AxFe3-xO4 coating on the magnetite core, where A is one of Co, Mn, Ni, Fe, Zn, Mg, or Cu.
An anisotropic magnetothermal nanoparticle comprising:
- a soft magnetic core having an anisotropic shape;
- and
- a hard magnetic coating on the soft magnetic core providing magnetic crystalline anisotropy via spin-exchange coupling effects at an interface between the soft magnetic core and the hard magnetic coating.
Dependencies are inferred from the claim text.