Ionizable lipid based on endogenous dicarboxylic acid as well as preparation method and use thereof

Abstract

An ionizable lipid based on endogenous dicarboxylic acid as well as a preparation method and use thereof. The ionizable lipid based on endogenous dicarboxylic acid is a compound represented by Formula (I), or a stereoisomer, tautomer, pharmaceutically acceptable salt or solvate thereof; wherein, X is selected from — Y is selected from —O— and —NH—; R is selected from C6-C20 alkyl, C6-C20 alkyl substituted by a substituent group, C6-C20 alkenyl, C6-C20 alkenyl substituted by a substituent group, C6-C20 alkynyl, and C6-C20 alkynyl substituted by a substituent group; n is an integer of 1-8.

Dependencies are inferred from the claim text.