Salts and solid state forms of a kif18a inhibitor compound
AssigneeAmgen Inc.
InventorsTian WU, Prashant AGARWAL, Andreas R. ROTHELI, Hyunsoo PARK, Michael J. FROHN
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Abstract
Disclosed herein is a salt, a crystalline anhydrous form, a hydrate, a solvate, or a co-crystal of a free base compound 2-(6-azaspiro[2.5]octan-6-yl)-N-[2-(4,4-difluoropiperidin-1-yl)-6-methylpyrimidin-4-yl]-4-[(2-hydroxyethanesulfonyl)amino]benzamide (Compound A); method of preparation, pharmaceutical compositions, and method of treating a disease mediated by a motor protein kinesin family member 18A (KIF18A) inhibition, wherein said disease is a neoplastic disease, including a cancer or a tumor.
Claims20
A salt, a hydrate, a solvate, or a co-crystal of Compound A having a chemical structure:
- or
- a solid form of Compound A, including crystalline anhydrous forms, salt, solvate, or co-crystal thereof.
Dependencies are inferred from the claim text.