Chromatography column adapters with face seals for interfacing with clamping fluidic connectors

Abstract

Threaded conventional column end fittings for liquid chromatography columns do not have face seals that enable them to be used with clamping fluidic connectors. The exemplary embodiments may provide adapters that interface with conventional threaded column end fittings so that the column assembly may now be used with the clamping fluidic connectors. The adapters of the exemplary embodiments may include lock nuts for securing the adapters to column end fittings of a liquid chromatography columns. The lock nuts may include threads that bear the load of the adapter rather than the column end fitting of the chromatography column. The threads of the lock nut become the load bearing surfaces, and the load is distributed over the surfaces where the threads of the adapter engage with the threads of the lock nut.

Dependencies are inferred from the claim text.