Trap1 inhibitor and use thereof
AssigneesSmartin Bio Inc., Unist (Ulsan National Institute of Science and Technology)
InventorsByoung Heon KANG, So-Yeon KIM, Nam Gu YOON
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Abstract
The present application provides a compound that inhibits TRAP1 or a pharmaceutically acceptable salt thereof. In this case, the compound or the pharmaceutically acceptable salt thereof can inhibit the binding between TRAP1 and the client protein. In addition, the present application provides: a pharmaceutical composition for the treatment of cancer or ocular disease comprising a compound that inhibits TRAP1 or a pharmaceutically acceptable salt thereof; and use thereof.
Claims23
A compound represented by following Formula 1 or a pharmaceutically acceptable salt thereof:
- Wherein,
- L comprises (CH2)n;
- n is an integer of 7 or more and 40 or less;
- and
- A is selected from methyl, unsubstituted or substituted aryl, unsubstituted or substituted cycloalkyl, and unsubstituted or substituted heterocyclyl.
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Dependencies are inferred from the claim text.