Methods for isolating dna from a blood sample
AssigneeBiocaptiva Limited
InventorsMark Bradley, Matthew Owens
Life of this patent
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Abstract
The present invention relates to methods for isolating nucleic acids present in a sample, in particular cell-free DNA (cfDNA) from a blood sample and polymers, substrates and kits for the method. Polymers with characteristics suitable to bind such nucleic acids are provided.
Claims20
A nucleobase containing polymer comprising a polymer backbone with at least a portion of side chains being nucleobase side chains, wherein the polymer further comprises positively charged moieties at physiological pH adapted to electrostatically interact with nucleic acids, and/or the polymer is adapted to interact with nucleic acids via hydrogen bonding.
Dependencies are inferred from the claim text.