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US 2024/0293326 A1Published application
Controlled release formulations for the treatment of malaria
AssigneeKarici Diagnostics Inc.
InventorsMircea-Alexandru MATEESCU, Kouadio Victorien KONAN
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Abstract
The present disclosure relates to a controlled release complex of a carboxylated polymer having carboxyl groups having a degree of substitution of about 0.1 to about 1.0, forming a complex through ionic interaction with an antimalarial alkaloid extract; a solid oral dosage form comprising the same, and a solid oral dosage form comprising an antimalarial drug combination which comprises the controlled release complex of the present invention and an antimalarial drug.
Claims18
A controlled release complex comprising:
- a carboxylated polymer having carboxyl groups having a degree of substitution of about 0.1 to about 1.0, forming a complex through ionic interaction with a first antimalarial alkaloid extract from Peschiera fuchsiaefolia, wherein said carboxylated polymer and said antimalarial alkaloid extract are present in a ratio of from about 10:90 to about 1:99.
Dependencies are inferred from the claim text.