Plasmonic nanoparticle platform for analyte detection
OwnerGuandong ZHANG, Zhiguo ZHOU +1inventors
InventorsGuandong ZHANG, Zhiguo ZHOU, Fang LIU
Life of this patent
Estimating the term…
Abstract
Described herein are compositions and methods for the rapid detection of target analytes on surfaces and in solutions using colorimetric analysis. In some embodiments, the compositions and methods may include plasmonic nanoparticles, a binding receptor conjugated or adsorbed to a surface of the nanoparticles, and a polymer-ligand conjugate. In some embodiments, the target analytes may include one or more opioids.
Claims22
A system for colorimetric detection of a target analyte, the system comprising:
- plasmonic gold nanoparticles (GNPs);
- a binding receptor conjugated or adsorbed to a surface of the GNPs;
- and
- a polymer-ligand conjugate, wherein the polymer is a polymer that stabilizes dispersion of the GNPs in a solution.
(canceled)
(canceled)
A method for colorimetric detection of a target analyte, the method comprising:
- contacting one or more surfaces or solutions with a system comprising:
- plasmonic gold nanoparticles (GNPs);
- a binding receptor conjugated or adsorbed to a surface of the GNPs;
- and
- a polymer-ligand conjugate;
- and
- detecting emergence of a color wavelength or detecting a color change on the one or more surfaces or solutions, indicating existence of the target analyte.
21-36. (canceled)
A kit for colorimetric detection of a target analyte, the kit comprising:
- a system comprising:
- plasmonic gold nanoparticles (GNPs);
- a binding receptor conjugated or adsorbed to a surface of the GNPs;
- a polymer-ligand conjugate;
- and
- one or more salts;
- a system applicator;
- optionally, a detection device;
- optionally, one or more articles of personal protective equipment;
- optionally, one or more buffers or receptacles;
- and
- optionally, one or more of packaging or instructions for use.
Dependencies are inferred from the claim text.