Cell-culture platform and a magnetic material for such a platform
AssigneesNational University of Singapore, Rexadvance Technology Pte. Ltd.
InventorsBoon Chuan LOW, Somsubhro MUKHERJEE, Qing LI, Ying Ming, Ivan YOW
Life of this patent
Estimating the term…
Abstract
A magnetic material for a cell-culture platform is disclosed herein. In a specific embodiment, the magnetic material comprises an elastomeric material and a dispersion of a plurality of magnetic particles embedded in the elastomeric material. A cell-culture platform including the magnetic material and a method of fabricating the magnetic material are also disclosed.
Claims33
Magnetic material for a cell-culture platform, comprising:
- an elastomeric material and a dispersion of a plurality of magnetic particles embedded in the elastomeric material.
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
A method of producing a magnetic material for a cell-culture platform, comprising:
- mixing a predetermined weight of magnetic particles into a quantity of a liquid elastomer to disperse the magnetic particles in the quantity of the liquid elastomer;
- and curing the quantity of the liquid elastomer to form the magnetic material.
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
A method of deforming cells using a cell-culture platform comprising a biocompatible deformable receptacle for cell-culture media, and
- a deformation actuator attached to the biocompatible deformable receptacle, the deformation actuator comprising an elastomeric material and a dispersion of a plurality of magnetic particles embedded in the elastomeric material, the method comprising:
- applying a cell-binding coating to an inner surface of the biocompatible deformable receptacle;
- seeding one or more cells onto the cell-binding coating;
- and
- attracting the dispersion of the plurality of magnetic particles using an applied magnetic field to deform the biocompatible deformable receptacle and the one or more cells.
Dependencies are inferred from the claim text.