Methods of coating substrates
AssigneeGlycome Biopharma Limited
InventorsEoin Scanlan, Graham Smith, Silvia Fogli, Anna Testolin, Paula Colavita
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Abstract
A method of coating a substrate surface, the method comprising: providing a substrate having a surface, optionally, treating at least a portion of the substrate surface with an oxidising agent, treating at least a portion of the substrate surface with a composition comprising a polysaccharide, oligosaccharide, polyol or mixture thereof, and incubating the treated substrate with the composition for a predetermined time. Also disclosed are substrates comprising such a coating, vessels comprising such coated substrates and medicals devices comprising such substrates.
Claims21
-32. (canceled)
A method of coating a substrate, the method comprising;
- a) providing a substrate having a surface,
- b) optionally, treating at least a portion of the substrate surface with an oxidising agent,
- c) treating at least a portion of the substrate surface with a composition comprising a polysaccharide, oligosaccharide, polyol or mixture thereof, and
- d) incubating the treated substrate with the composition for a predetermined time.
A substrate having a coating on at least one surface, the coating comprising a polysaccharide, oligosaccharide, polyol or mixture thereof directly contacting the surface of the substrate, wherein the substrate comprises quartz or glass.
A method of reducing protein or oligonucleotide aggregation and/or adsorption on a substrate surface, the method comprising,
- a) providing a substrate having a surface coating, the substrate comprising quartz or glass, and the surface coating comprising a polysaccharide, oligosaccharide, polyol or mixture thereof directly contacting the surface of the substrate;
- and
- b) contacting the surface with a proteinaceous composition or a composition comprising an oligonucleotide.
Dependencies are inferred from the claim text.