Devices and Methods for Modifying Optical Properties
AssigneePfizer Inc.
InventorsFrank B. Myers, III, Debkishore Mitra, John Robert Waldeisen, Ivan Krastev Dimov
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Abstract
Devices and methods for modifying optical properties of biological samples or aspects thereof are provided. The subject methods include generating a reaction product with a device and reacting the reaction product to sufficiently modify an optical property to allow detection of the modified optical property.
Claims49
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A method of modifying an optical property in a biological sample assay, the method comprising:
- a. transmitting a biological sample into one or more reaction chambers of a sample receiving cartridge of a biological sample assay optical property modifying device, wherein the chambers comprise an optical property modifying reagent, thereby generating a reaction mixture;
- b. heating the reaction mixture with a heating element of the device and thereby generating a reaction product;
- and
- c. reacting the reaction product with the optical property modifying reagent, wherein the reacting sufficiently modifies an optical property of the optical property modifying reagent to allow detection of the modified optical property.
A method of modifying an optical property with a biological sample assay optical property modifying device, the method comprising:
- a. generating a reaction product from a biological sample;
- b. reacting the reaction product with an optical property modifying reagent, wherein the reacting sufficiently modifies an optical property of the optical property modifying reagent to allow detection of the modified optical property.
A method of manufacturing a biological sample assay optical property modifying device, the method comprising:
- operatively coupling a sample receiving cartridge and a substrate with an adhesive layer.
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Dependencies are inferred from the claim text.