Method for detecting anti-sars-cov-2 antibody, chimeric protein, polynucleotide, expression vector, host cell, method for producing chimeric protein, and reagent

Abstract

Disclosed is a method for detecting an anti-SARS-CoV-2 antibody, the method comprising: detecting an antibody against a chimeric protein comprising an amino acid sequence of a receptor binding region of SARS-CoV-2 and an amino acid sequence of a receptor binding region of a coronavirus belonging to Nobecovirus subgenus in a specimen obtained from a subject using the chimeric protein, the chimeric protein being a protein represented by (i) a protein comprising an amino acid sequence set forth in SEQ ID NO: 1 or 2; or (ii) a protein comprising an amino acid sequence having 80% or more of identity to the amino acid sequence set forth in SEQ ID NO: 1 or 2 and binding to an antibody that recognizes the receptor binding region of SARS-CoV-2.

Dependencies are inferred from the claim text.