Compositions and methods for treating neurodegenerative diseases by inhibiting fsh
AssigneesIcahn School of Medicine at Mount Sinai, Emory University
InventorsMone Zaidi, Keqiang Ye
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Abstract
The present disclosure provides compositions and methods for treating neurodegenerative diseases, in particular, Alzheimer's Disease, by inhibiting FSH in a subject in need thereof. A method comprising of treating Alzheimer's Disease (AD), preventing the onset of AD, or reducing cognitive or functional decline in AD, in a subject in need or at risk thereof.
Claims24
A method of treating Alzheimer's Disease (AD), preventing the onset of AD, or reducing cognitive or functional decline in AD, in a subject in need or at risk thereof, comprising administering to said subject a therapeutically effective amount of a composition comprising an FSH-inactivating agent.
The method of any one of the preceding claims, wherein the FSH-inactivating agent is administered intravenously, intrathecally, intracranially, cutaneously, subcutaneously, intraperitoneally, intramuscularly, orally, topically, transdermally, nasally, or rectally to the subject.
The method of claim 24, wherein the anti-FSH antibody is a polyclonal antibody.
Dependencies are inferred from the claim text.