Systems and methods of using nanomembrane electronics
AssigneesGeorgia Tech Research Corporation, Emory University
InventorsWoon-Hong YEO, Hyojung J. CHOO
Life of this patent
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Abstract
Described herein are wireless nanomembrane non-invasive system that integrates skin-wearable printed sensors and electronics and methods that can be used to monitor an electrophysiological parameter of a subject or to identify a therapeutic agent. The systems can include wearable devices, including skin-wearable printed sensors; and electronics for real-time, continuous monitoring of electrophysiological parameters of a subject.
Claims23
-12. (canceled)
An animal model system, comprising:
- an animal subject comprising a wearable device comprising a skin-wearable printed sensor over the animal subject's skin, wherein the animal subject was administered an agent of interest, was subjected to an injury, or any combination thereof;
- the skin-wearable printed sensor comprises one or more stretchable graphene sensors configured as a sensor selected from the group consisting of electrical sensor, impedance sensor, infrared sensor, electrocardiogram (ECG) sensor, an electroencephalogram (EEC) sensor, an electromyogram (EMG) sensor, or any combination thereof, wherein the skin-wearable printed sensor is used to monitor an electrophysiological parameter of a subject.
-20. (canceled)
A method for monitoring an electrophysiological parameter of a subject, the method comprising:
- acquiring signals from a wearable device comprising a skin-wearable printed sensor over a subject's skin;
- and
- assessing disease progression on the subject, an injury on the subject, or any combination thereof using the acquired signals to provide real-time, continuous monitoring of the electrophysiological parameter of a subject.
-31. (canceled)
A method of identifying therapeutic agent, the method comprising:
- contacting a wearable device comprising a skin-wearable printed sensor with a subject's skin;
- acquiring signals from the wearable device on the subject's skin;
- administering an agent of interest to the subject;
- acquiring signals from the wearable device on the subject's skin following administration of the agent of interest;
- comparing the signals of the subject before and after administration of the agent of interest;
- and
- analyze a result from the comparison step to assess a physiological parameter of the subject;
- wherein the physiological parameter provides an indication that the agent of interest is a therapeutic agent.
-39. (canceled)
-64. (canceled)
Dependencies are inferred from the claim text.