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US 2024/0245809 A1Published application
A contrast agent for mri imaging diagnostics
AssigneeCatharina Philippina Janssen
InventorsCatharina Philippina Janssen, Jelle Onno Barentsz, James Nagarajah, Vasant Kumar, Rumen Tomov
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Abstract
A contrast agent for MRI imaging diagnostics. The contrast agent is comprised of a nano-fuel cell coupled to at least one ligand for specific binding to a cell membrane. An imaging method for the visualisation of tumor cells using the contrast agent and a method for non invasive treatment of tumor cells using the contrast agent.
Claims19
A contrast agent for MRI imaging diagnostics comprised of a nano fuel cell coupled to at least one ligand for specific binding to a cell membrane,
- wherein the nano fuel cell is comprised of an anode compartment including an anode, a cathode compartment including a cathode, and a suspension for generating a current of electrons,
- wherein said suspension is preferably comprised of a plurality of hollow particles in electrically conductive contact,
- wherein said hollow particles comprise entrapped therein a redox-reaction for catalyzing an enzymatic conversion of a substrate in said hollow particles thereby liberating electrons, and
- wherein said hollow particles comprise a substrate permeable and electrically conductive outer polymer shell, and said suspension is disposed within said anode compartment, or within said cathode compartment, or between said anode and cathode compartment.
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Dependencies are inferred from the claim text.