Composite gel for removing residual stone fragments after lithotripsy
AssigneeXiaochen Zhou
InventorsXiaochen Zhou, Renrui Kuang, Haibo Xi, Yue Yu, Jun Deng, Yujun Chen, Xinpeng Chen
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AssigneeXiaochen Zhou
InventorsXiaochen Zhou, Renrui Kuang, Haibo Xi, Yue Yu, Jun Deng, Yujun Chen, Xinpeng Chen
Estimating the term…
A composition gel for surgical efficiency improvement of urinary stone lithotripsy and stone fragments removal in renal collecting system includes component A and component B. The component A contains fibrinogen and fibrin stabilizing factors. The component B contains thrombin. Moreover, at least one of the components A and B contains Ca2+, plasminogen and a coloring agent. The composition gel may quickly form plasminogen-containing fibrin gel with color, and certain toughness and plasticity in urine and normal saline environments, may adhere to and wrap stone fragments in such environments, and is removed by negative pressure suction and/or stone basket. The composition gel is suitable for efficiently removing stone fragments which remain after lithotripsy and are unable to be removed by an effective method at present. It has good biosafety, and achieves stone clearance rate of more than 85% without damage to the kidney and surgical instruments. The fibrin gel may be naturally dissolved in urine without the risk of urinary system obstruction.
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