Fluid stimulation methods and devices for treating fluid overload

A fluid stimulation system for treating fluid overload in a subject, the system comprising:

• a wearable apparatus comprising a chamber sized to fit around a body part of a subject, wherein at least a portion of the chamber provides a clear volume of air between the body part of the subject and one or more walls of the chamber upon receipt of air flow and subsequent expansion of the chamber, the chamber comprising an inlet and an outlet and the chamber being configured such that an air flow passes through the chamber from the inlet to the outlet to create a controlled environment around the body part of the subject for stimulating fluid loss in the subject;
• one or more sensors for measuring at least temperature of incoming air flowing into the chamber;
• and
• a controller communicatively coupled with the one or more sensors and configured to receive temperature measurements therefrom, wherein the controller is configured to adjust temperature and flow rate of incoming air flowing into the chamber based, at least in part, on the received temperature measurements to thereby:
• maintain a temperature of at least incoming air flowing into the chamber at the inlet to be within 1.5° C. of a set temperature parameter between 32° C. and 50° C.;
• maintain a relative humidity of the environment within the chamber at less than 60% to thereby allow removed fluids on the subject's skin to evaporate and cool the subject's core temperature while avoiding accumulation of fluids within the chamber;
• and
• maintain a skin temperature the subject between 35° C. and 40° C. to initiate and maintain perspiration and stimulate fluid loss.