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US 2024/0230665 A9Published application
Generation of human allergen- and helminth-specific ige monoclonal antibodies for diagnostic and therapeutic use
AssigneeVanderbilt University
InventorScott A. SMITH
Life of this patent
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Abstract
The present disclosure is directed to human monoclonal IgE antibodies, and IgG antibodies engineered therefrom. Such engineered antibodies can be used to blunt pathologic IgE responses in subjects, such as in the treatment or prevention of allergies.
Claims11
A pharmaceutical composition comprising:
- a therapeutically effective amount of an antibody or a fragment thereof, wherein the antibody or the fragment thereof binds a food allergen;
- and
- a pharmaceutically acceptable carrier.
Dependencies are inferred from the claim text.