Inhibitors of Tryptases and Their Use in Treating Allergies
AssigneeThe Board of Trustees of the Leland Stanford Junior University
InventorsVinit MAHAJAN, Young Joo SUN, Soo Hyeon LEE, Gabriel VELEZ
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Abstract
Methods are provided for treating allergies, asthma, or mast cell activation syndrome with a tryptase inhibitor. In particular, methods of treating allergies, asthma, or mast cell activation syndrome with the tryptase inhibitor, Avoralstat, are disclosed.
Claims13
1-6. (canceled)
A method of treating a subject for an allergy, asthma, or mast cell activation syndrome, the method comprising administering a therapeutically effective amount of a composition comprising a tryptase inhibitor to the subject.
A method of inhibiting tryptase b2 or tryptase g1, the method comprising contacting tryptase b2 or tryptase g1 with Avoralstat.
Dependencies are inferred from the claim text.