Systems and techniques for in-source ion separation
AssigneeThermo Finnigan LLC
InventorMikhail V. Ugarov
Life of this patent
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Abstract
Systems, devices, and methods for in-source ion separation are provided. An ion separator includes an ion transfer conduit fluidically upstream of and coupled with one or more components of an analytical instrument. The ion separator includes a gas conduit, fluidically upstream of and coupled with the ion transfer conduit, the gas conduit defining an internal volume. The ion separator also includes electronic circuitry defining an active surface exposed to the internal volume, the electronic circuitry being configured to energize the active surface. Embodiments of the present disclosure provide improved analysis of material samples based at least in part on in-source separation of relatively light ions from relatively heavy ions entrained in a gas flow.
Claims20
An ion separator for in-source ion separation, comprising:
- an ion transfer conduit fluidically upstream of and coupled with one or more components of an analytical instrument;
- a gas conduit, fluidically upstream of and coupled with the ion transfer conduit, the gas conduit defining an internal volume;
- and
- electronic circuitry defining an active surface exposed to the internal volume, the electronic circuitry being configured to energize the active surface.
An analytical instrument, comprising:
- an ion source configured to generate a stream of ionized sample material;
- a gas conduit, fluidically coupled with the ion source and oriented to receive the stream of ionized sample material from the ion source, the gas conduit defining an internal volume;
- electronic circuitry defining an active surface exposed to the internal volume, the electronic circuitry being configured to energize the active surface;
- an ion transfer conduit downstream of and fluidically coupled with the ion source via the gas conduit;
- and
- one or more components of the analytical instrument configured to receive ions of the stream of ionized sample material and to generate spectrometric data characteristic of the ionized sample material.
Dependencies are inferred from the claim text.