Recombinant yeasts for producing acetone and/or isopropanol from fatty acid feedstocks
AssigneeCircular Industries Holding Pte Ltd.
InventorJosé Miguel Laplaza
Life of this patent
Estimating the term…
Abstract
Recombinant yeasts bioengineered to overexpress genes for utilization of fatty acids to produce acetone and isopropanol, and methods of use thereof. The yeasts are modified to express, constitutively express, or overexpress an acetyl-CoA thioesterase, an acetyl-CoA C-acetyltransferase, an acetoacetyl-CoA transferase, an acetoacetyl-CoA thioesterase, an acetoacetate decarboxylase, an isopropanol dehydrogenase, or any combination thereof. The methods include cultivating the recombinant yeasts to convert any fatty acid-containing feedstocks into acetone and/or isopropanol.
Claims27
A recombinant yeast comprising one or more recombinant genes, wherein the one or more recombinant genes are configured to express any one or more enzymes selected from the group consisting of an acetyl-CoA thioesterase, an acetyl-CoA C-acetyltransferase, an acetoacetyl-CoA transferase, an acetoacetyl-CoA thioesterase, an acetoacetate decarboxylase, and an isopropanol dehydrogenase.
Dependencies are inferred from the claim text.