Attenuated salmonella gallinarum strain and use thereof
AssigneesIndustry Foundation of Chonnam National University, Odysseus Bio Co., Ltd.
InventorsHyon El CHOY, Kwangsoo KIM, Jae Ho JEONG, Dae Jin LIM, Taner DUYSAK, Quang Thanh TRAN
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Abstract
The present invention relates to an attenuated Salmonella gallinarum strain and use thereof. Particularly, the present invention relates to: a novel attenuated Salmonella strain in which all of a gene encoding guanosine tetraphosphate (ppGpp) synthetase, a gene that induces the function of a type III secretion system (T3SS)(ssrAB), and a Gifsy 2prophage gene are deleted; and a composition for treating or diagnosing tumors by using same.
Claims17
An attenuated Salmonella gallinarum strain in which a gene encoding guanosine tetraphosphate (ppGpp) synthetase, a gene inducing the function of a type III secretion system (T3SS), and a Gifsy 2 prophage gene are deleted.
Dependencies are inferred from the claim text.