Bromelain protease, bromelain, jacalin-like lectin, extract from the stem and/or the fruit of a pineapple plant, combination preparation, bromelain protease inhibitor, protein/protease mix, and glycated bromelain protein formed by exogenous non-enzymatic glycation, for use in the treatment or prophylaxis of virus infections caused by coronaviruses in a human or animal

A method of treating a human or animal infected by a coronavirus, or providing prophylaxis against a coronavirus infection, the method comprising administering to the human or animal an effective amount of a compound selected from the group consisting of bromelain protease, a jacalin-related lectin, a combination preparation of a bromelain protease and a jacalin-related lectin, an extract from the stem and/or from the fruit of a pineapple plant, a bromelain protease inhibitor comprising at least one peptide having an amino acid sequence that is at least 90% identical with one of the sequences of SEQ ID NO:

• 1-7, a glycated bromelain protein, and a bromelain protease mixture, which is a peptide mass, wherein the bromelain protease mixture contains less than 5.0% (w/w) bromelain protease inhibitors in the peptide mass.

A glycated bromelain protein produced by exogenous non-enzymatic glycation, comprising at least one sugar unit covalently bound to a bromelain protein.