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US 2024/0215579 A1Published application
Use of anti-clotting compounds as rodenticides
OwnerDietrich GULBAinventor
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Abstract
The present invention proposes a composition for controlling pest rodents, the composition comprising: a) at least one direct coagulation factor inhibitor and b) at least one P-glycoprotein inhibitor (p-GP inhibitor). Through the composition, it is possible to achieve that existing resistances in pest rodents can be circumvented and at the same time a good effect can be achieved with a lower dosage, which can result in a comparatively more environmentally friendly application.
Claims18
A composition for controlling pest rodents, characterized in that the composition has:
- a) at least one direct clotting factor inhibitor, and
- b) at least one P-glycoprotein inhibitor (Pgp inhibitor), characterized in that the P-glycoprotein inhibitor (Pgp inhibitor) is at least one compound selected from the group consisting of amiodarone, dronedarone, diltiazem, verapamil, atorvastatin, rosuvastatin, lovastatin, simvastatin, clarithromycin, roxithromycin, erythromycin, moxifloxacin, ofloxacin, fluconazole, voriconazole, itraconazole, mefloquine, quinidine, ritonavir, nefinavir, saquinavir, elacridar, tamoxifen, cyclosporin, tacrolimus, ciclosporin, lansoprazole, omeprazole and ondansetron.
Dependencies are inferred from the claim text.