Methods for deposition of chitosan coating on urinary catheters
AssigneeJozef Stefan Institute
InventorsAlenka VESEL, Miran MOZETIC, Gregor PRIMC, Rok ZAPLOTNIK, Albert KURINCIC
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AssigneeJozef Stefan Institute
InventorsAlenka VESEL, Miran MOZETIC, Gregor PRIMC, Rok ZAPLOTNIK, Albert KURINCIC
Estimating the term…
The aspects of the disclosed embodiments relates to methods for optimization of the sliding properties of urinary catheters. The urinary catheters are first treated with a non-equilibrium gaseous plasma sustained in reactive gases or a mixture of a reactive gas with a noble gas. The first treatment enables a hydrophilic surface finish when oxygen is a reactive gas and an almost super-hydrophilic finish when the catheter is treated with hydrogen plasma followed by oxygen plasma. The hydrophilicity of the surface finish obtained upon the first plasma treatment is beneficial for adhering a layer of water solution of chitosan, which spreads uniformly on the entire outer surface of the catheter. The catheter with a layer of water solution of chitosan is dried and then treated with plasma containing an oxidative gas for better absorption of water by the dried chitosan film.
A method for preparation of chitosan-coated catheters comprising the following steps:
A chitosan-coated catheter, wherein the chitosan layer on the catheter is highly wettable and the water contact angle is around 50° or lower, preferably 40°±5° or lower.
Dependencies are inferred from the claim text.