# US 2024/0201180 A1 · Platinum electrode system > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 2024/0201180 A1 - Document ID: US20240201180A1 - Status: Published application - Kind: A1 - Application number: 18/068,219 - Filed: 2022-12-19 - Published: 2024-06-20 - Earliest claimed: 2022-12-19 - Assignees: Dionex Corporation - Applicants: Dionex Corporation - Inventors: Jun Cheng; Yan Liu; Arshdeep Kaur - Web page: https://patentgrep.com/patent/US20240201180A1 ## CPC - G01N 33/5438: {Electrodes} - G01N 27/301: {Reference electrodes} - G01N 27/3273: {Devices therefor, e.g. test element readers, circuitry (details not specific to biochemical electrodes G01N33/4875)} - G01N 27/4045: {for gases other than oxygen} - G01N: INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES (measuring or testing apparatus or processes other than immunoassay, involving enzymes or microorganisms C12M, C12Q) ## Abstract A detection cell for a chromatography system, the detection cell includes a cell body including a counter electrode in the form of the cell body or a wire; a working electrode block including a working electrode; a gasket separating the working electrode block from the cell body, the gasket defining a sample flow pathway extending between an inlet and an outlet of the detection cell and in fluid contact with the cell body, the counter electrode, and the working electrode; and a reference electrode system in fluidic contact with the outlet and including a platinum auxiliary electrode operably connected to a positive pole of a power supply and a platinum reference electrode operably connected to a negative pole of the power supply. ## Claims ### Claim 1 A detection cell for a chromatography system, the detection cell comprising: a cell body including a counter electrode in the form of the cell body or a wire; a working electrode block including a working electrode; a gasket separating the working electrode block from the cell body, the gasket defining a sample flow pathway extending between an inlet and an outlet of the detection cell and in fluid contact with the cell body, the counter electrode, and the working electrode; and a reference electrode system in fluidic contact with the outlet and including a platinum auxiliary electrode operably connected to a positive pole of a power supply and a platinum reference electrode operably connected to a negative pole of the power supply. ### Claim 2 (depends on 1) A detection cell according to claim 1, wherein the detection cell is a three-electrode detection system. ### Claim 3 (depends on 1) A detection cell according to claim 1, wherein the cell body is formed of a conductive material or nonconductive material. ### Claim 4 (depends on 1) A detection cell according to claim 1, wherein the cell body is formed of a corrosion resistant metal or a conductive polymer and a nonconductive polymer. ### Claim 5 (depends on 4) A detection cell according to claim 4, wherein the cell body is formed of a conductive material selected from the group consisting of titanium, corrosion resistant alloy, stainless steel, carbon-loaded polyetherether ketone (PEEK), polythiophene, polyindole, and polynaphtalene while a nonconductive material selected from the group consisting of polytetrafluoroethylene (PTFE), polyetheretherketone (PEEK), polychlorotrifluoroethylene (Kel-F), polycarbonate. ### Claim 6 (depends on 1) A detection cell according to claim 1, wherein the reference electrode system includes a solid state reference electrode. ### Claim 7 (depends on 1) A detection cell according to claim 1, wherein the platinum reference electrode and the Pt auxiliary electrode are in electrical contact with the fluid sample passageway. ### Claim 8 (depends on 7) A detection cell according to claim 7, wherein the reference electrode includes a wire extending into a reference electrode bore of the cell body. ### Claim 9 (depends on 1) A detection cell according to claim 1, wherein the cell body includes an electrode cavity fluidly connected to the inlet and the outlet thereby forming a portion of the fluid sample passageway. ### Claim 10 (depends on 9) A detection cell according to claim 9, wherein at least one of the Pt/H2 reference electrode and the platinum auxiliary electrode is a wire. ### Claim 11 (depends on 1) A chromatography system comprising the detection cell according to claim 1. ### Claim 12 (depends on 9) A chromatography system comprising the detection cell according to claim 9. ### Claim 13 (depends on 1) A chromatography system comprising a plurality of detection cells according to claim 1, wherein the detection cells are arranged in series. ### Claim 14 A detection cell for a chromatography system, the detection cell comprising: a cell body; a working electrode block including a working electrode; a sample channel extending between an inlet and an outlet of the detection cell and in fluid contact with the cell body and the working electrode; a counter electrode in fluid contact with the sample channel; and a reference electrode system in fluidic contact with the outlet and including an auxiliary electrode operably connected to a positive pole of a power supply and a Pt/H2 reference electrode operably connected to a negative pole of the power supply. ### Claim 15 (depends on 14) A detection cell according to claim 14, wherein the cell body is formed of a conductive material. ### Claim 16 (depends on 14) A detection cell according to claim 14, wherein the Pt/H2 reference electrode and the auxiliary electrode are in electrical contact with the sample channel, and in which the auxiliary electrode includes a platinum electrode. ### Claim 17 (depends on 14) A detection cell according to claim 14, wherein the Pt/H2 reference electrode includes a wire extending into a reference electrode bore of the cell body. ### Claim 18 (depends on 14) A detection cell according to claim 14, wherein the reference electrode system operates at a potential less than approximately 10V subject to variations in voltage of less than approximately 10 mV. ### Claim 19 (depends on 14) A detection cell according to claim 14, wherein the channel has a volume of approximately 1 pL to 100 μL.