# US 2024/0198104 A1 · Brain stimulation system including multiple stimulation modes

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- Number: US 2024/0198104 A1
- Document ID: US20240198104A1
- Status: Published application
- Kind: A1
- Application number: 18/357,817
- Filed: 2023-07-24
- Published: 2024-06-20
- Earliest claimed: 2014-08-14
- Assignees: Functional Neuromodulation, Inc.
- Applicants: Functional Neuromodulation, Inc.
- Inventors: J. Christopher Flaherty; Daniel J. O'Connell; Todd Langevin; R. Maxwell Flaherty
- Web page: https://patentgrep.com/patent/US20240198104A1

## CPC

- A61N 1/36082: {Cognitive or psychiatric applications, e.g. dementia or Alzheimer's disease}
- A61B 5/02055: {Simultaneously evaluating both cardiovascular condition and temperature}
- A61B 5/021: Measuring pressure in heart or blood vessels
- A61B 5/0531: Measuring skin impedance
- A61B 5/1118: {Determining activity level}
- A61B 5/14532: {for measuring glucose, e.g. by tissue impedance measurement}
- A61B 5/14539: {for measuring pH}
- A61B 5/14542: {for measuring blood gases (A61B5/14551 takes precedence)}
- A61B 5/14546: {for measuring analytes not otherwise provided for, e.g. ions, cytochromes}
- A61B 5/369: Electroencephalography [EEG]
- A61B 5/4064: {Evaluating the brain (for intracranial pressure A61B5/031; for cerebral blood gases A61B5/14553; using EEG A61B5/369)}
- A61B 5/4076: {Diagnosing or monitoring particular conditions of the nervous system}
- A61B 5/4806: {Sleep evaluation (A61B5/4821 takes precedence; devices for inducing sleep A61M21/02)}
- A61B 5/4836: {Diagnosis combined with treatment in closed-loop systems or methods (A61B5/0036 takes precedence)}
- A61B 6/032: {Transmission computed tomography [CT]}
- A61B 6/037: {Emission tomography}
- A61B 6/487: {involving fluoroscopy}
- A61N 1/0531: {Brain cortex electrodes}
- A61N 1/0534: {Electrodes for deep brain stimulation}
- A61N 1/36064: {Epilepsy}
- A61N 1/36067: {Movement disorders, e.g. tremor or Parkinson disease (stimulating motor muscle A61N1/36003)}
- A61N 1/36096: {Mood disorders, e.g. depression, anxiety or panic disorder}
- A61N 1/36139: {with automatic adjustment}
- A61N 1/36146: {specified by the stimulation parameters}
- A61N 2/002: {in combination with another treatment}
- A61N 2/006: {for magnetic stimulation of nerve tissue}
- A61N 5/0622: {Optical stimulation for exciting neural tissue}
- A61N 7/00: Ultrasound therapy (lithotripsy A61B17/22, A61B17/225; massage using supersonic vibration A61H23/00 {; using ultrasound for introducing media into the body A61M37/0092})
- A61N 1/36121: {Production of neurotransmitters; Modulation of genes expression}
- A61N 2007/0026: {Stimulation of nerve tissue}
- A61N: ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY (measurement of bioelectric currents A61B; surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body A61B18/00; anaesthetic apparatus in general A61M; incandescent lamps H01K; infrared radiators for heating H05B)
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)

## Abstract

A system for treating a patient comprises a stimulator for stimulating brain tissue, a controller for setting stimulation parameters and a diagnostic tool for measuring patient parameters and producing diagnostic data. The stimulation parameters comprise test stimulation parameters and treatment stimulation parameters. The stimulator delivers test stimulation energy to the brain tissue based on at least one test stimulation parameter and delivers treatment stimulation energy to the brain tissue based on at least one treatment stimulation parameter. One or more treatment stimulator parameters are determined based on the diagnostic data produced by the diagnostic tool The system is constructed and arranged to treat a neurological disease or a neurological disorder. Methods of treating a neurological disease or neurological disorder are also provided.

## Claims

### Claim 1

A system for treating a patient, comprising:
a stimulator for stimulating brain tissue; and
a controller for setting stimulation parameters of the stimulator, wherein the stimulator is configured to operate in a first mode with a first set of stimulation parameters and a second mode with a second set of stimulation parameters different than the first set of stimulation parameters; and
wherein the system is configured to treat at least one of a cognitive disease or a cognitive disorder.