# US 2024/0197477 A1 · Fixing device for clamping tissue > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 2024/0197477 A1 - Document ID: US20240197477A1 - Status: Published application - Kind: A1 - Application number: 18/591,034 - Filed: 2024-02-29 - Published: 2024-06-20 - Earliest claimed: 2020-12-30 - Assignees: Sierra Valve LLC; Peijia Medical (Suzhou) Co., Ltd. - Applicants: Sierra Valve LLC; Peijia Medical (Suzhou) Co., Ltd. - Inventors: Kai Wang; Jian Fong Tan; Yi Zhang - Web page: https://patentgrep.com/patent/US20240197477A1 ## CPC - A61F 2/246: {Devices for obstructing a leak through a native valve in a closed condition} - A61F 2/2463: {Implants forming part of the valve leaflets} - A61F 2/2466: {Delivery devices therefor} - A61F 2220/0008: Fixation appliances for connecting prostheses to the body - A61F 2220/0041: using additional screws, bolts, dowels or rivets, e.g. connecting screws - A61F: FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS (dental prosthetics A61C) ## Abstract A fixing device for clamping a tissue comprises a support mechanism comprising a fixed connecting assembly and a drive assembly, and a clamp mechanism comprising closure members and capture portions, wherein each closure member comprises a closure connecting portion and a closure clamping portion in cooperation with one of the capture portions to clamp the tissue; wherein each closure connecting portion is provided with guide slots comprising a first slot portion and a second slot portion in communication therewith and has a relatively smaller radian, the fixed connecting assembly is provided with pins at least partially located in the guide slots, respectively, and the pins are slidable relative to the guide slots when the drive assembly moves relative to the fixed connecting assembly, so as to drive the closure clamping portions to move towards or away from each other. A system comprising the fixing device, and a method are provided. ## Claims ### Claim 1 A fixing device for clamping a tissue, comprising: a support mechanism comprising a fixed connecting assembly and a drive assembly movable relative to the fixed connecting assembly; and a clamp mechanism comprising closure members and capture portions which are in one-to-one correspondence with the closure members; wherein each of the closure members comprises a closure connecting portion and a closure clamping portion in cooperation with respective one of the capture portions to clamp the tissue; and wherein each of the closure connecting portions is provided with guide slots, each of the guide slots comprises, from a distal end to a proximal end thereof, at least a first slot portion and a second slot portion which is in communication with the first slot portion and has a radian smaller than that of the first slot portion, the fixed connecting assembly is provided with two pins at least partially located in the guide slots, respectively, and the fixed connecting assembly and the two closure connecting portions are arranged in such a manner that the two pins are slidable relative to the guide slots when the drive assembly moves relative to the fixed connecting assembly, so as to drive the two closure clamping portions of the clamp mechanism to move towards or away from each other. ### Claim 2 (depends on 1) The fixing device according to claim 1, wherein each of the pins are located at or near a proximal end of respective one of the guide slots when the closure clamping portions are closed. ### Claim 3 (depends on 1) The fixing device according to claim 1, wherein the first slot portions are arc segments, and the second slot portions are linear segments. ### Claim 4 (depends on 1) The fixing device according to claim 1, wherein each of the guide slots further comprises a third slot portion in communication with the respective second slot portion and having a radian greater than the radian of the respective second slot portion, and the second slot portions are located between the first slot portions and the third slot portions, respectively. ### Claim 5 (depends on 4) The fixing device according to claim 4, wherein the first slot portions and the third slot portions are arc segments, and the second slot portions are linear segments. ### Claim 6 (depends on 1) The fixing device according to claim 1, wherein the drive assembly comprises a drive connecting member, and side surfaces of the drive connecting member include first mounting surfaces and second mounting surfaces perpendicular to the first mounting surfaces; the drive connecting member is hinged to the closure connecting portion through a closure member matching portion on the first mounting surfaces. ### Claim 7 (depends on 1) The fixing device according to claim 1, wherein each one of the capture portions includes a rigid capture portion, a capture connecting portion and a flexible connecting portion located between the rigid capture portion and the capture connecting portion, and the second mounting surfaces are fixedly connected to respective one of the capture connecting portions. ### Claim 8 (depends on 4) The fixing device according to claim 4, wherein, when the closure clamping portions are in an unopen position, each of the pins is located at or near a most proximal end of corresponding one of the third slot portions. ### Claim 9 (depends on 8) The fixing device according to claim 8, wherein, when the closure clamping portions are rotated from the unopen position by a first angle, each of the pins is located at a joint of respective one of the second slot portions and respective one of the third slot portions. ### Claim 10 (depends on 8) The fixing device according to claim 8, wherein, when the closure clamping portions are rotated from the unopen position by a second angle, each of the pins is located at a joint of respective one of the second slot portions and respective one of the first slot portions. ### Claim 11 (depends on 8) The fixing device according to claim 8, wherein, when the closure clamping portions are rotated from the unopen position by a third angle, each of the pins is located at or near a most distal end of respective one of the first guide slots. ### Claim 12 (depends on 1) A system for clamping a tissue, comprising the fixing device according to claim 1; a delivery control device comprising a shaft for introducing the fixing device to a target location and a grasping mechanism for enabling the shaft and the fixing device to be separably connected. ### Claim 13 (depends on 1) A method for clamping tissues by using the fixing device according to claim 1, comprising: delivering the fixing device to a target location; adjusting the closure members of the fixing device to approach/contact the tissues controlling the capture portions of the fixing device so as to clamp the tissues between the closure members and the capture portions; and adjusting the closure members to a right position before the fixing device self-locks. ### Claim 14 (depends on 13) The method according to claim 13, wherein the closure members of the fixing device are in a closed state in the step of delivering the fixing device to a target location. ### Claim 15 (depends on 13) The method according to claim 13, wherein the step of adjusting the closure members of the fixing device to approach/contact the tissues comprises pivoting the closure members of the fixing device to locate the tissues between the closure members and the capture portions of the fixing device. ### Claim 16 (depends on 15) The method according to claim 15, wherein, during the step of pivoting the closure members of the fixing device to locate the tissues between the closure members and the capture portions of the fixing device, the pins are displaced relative to the guide slots such that the two closure clamping portions move away from each other.