# US 2024/0197331 A1 · Medical device and system with enhanced echogenicity and method thereof > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 2024/0197331 A1 - Document ID: US20240197331A1 - Status: Published application - Kind: A1 - Application number: 18/082,524 - Filed: 2022-12-15 - Published: 2024-06-20 - Earliest claimed: 2022-12-15 - Assignees: Coherex Medical, Inc. - Applicants: Coherex Medical, Inc. - Inventors: Sung K. Lee; Tom Ditter; Annabel Lee - Web page: https://patentgrep.com/patent/US20240197331A1 ## CPC - A61B 17/12122: {within the heart (for closing a cardiac septal defect A61B17/0057)} - A61B 17/12172: {having a pre-set deployed three-dimensional shape (methods of manufacturing A61B2017/00526)} - A61B 17/12177: {comprising additional materials, e.g. thrombogenic, having filaments, having fibers or being coated} - A61L 31/048: {obtained by reactions only involving carbon-to-carbon unsaturated bonds (A61L31/041 takes precedence)} - A61L 31/06: obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds {(A61L31/041 takes precedence)} - A61L 31/148: {Materials at least partially resorbable by the body} - A61B 2017/00004: {(bio)absorbable, (bio)resorbable or resorptive} - A61B 2017/00526: {Methods of manufacturing} - A61B 2017/00632: {Occluding a cavity, i.e. closing a blind opening} - A61B 2017/00676: {promotion of self-sealing of the puncture} - A61B 2017/00871: {polymeric} - A61B 2017/00884: {enhancing wound closure} - A61B 2017/00942: {hydrophilic} - A61B 2017/1205: {Introduction devices} - A61B 2017/12054: {Details concerning the detachment of the occluding device from the introduction device} - A61B 2090/3925: {ultrasonic} - A61L 2430/36: for embolization or occlusion, e.g. vaso-occlusive compositions or devices - A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D) - A61L: METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES (preservation of bodies or disinfecting characterised by the agents employed A01N; preserving, e.g. sterilising, food or foodstuffs A23; preparations for medical, dental or toiletry purposes A61K) ## Abstract A medical device configured to be percutaneously delivered to a heart with a catheter of a medical device delivery system. The medical device including a framework and tissue growth member. The framework includes a hub with frame segments extending radially from the hub. The tissue growth member is attached to the framework and extends radially along the framework such that the tissue growth member extends to define an outer layer portion and an inner layer portion where the framework is coupled to the inner layer portion. Further, the tissue growth member extends with multiple voids defined therein such that a filler material is configured to temporarily fill the multiple voids of the tissue growth member. ## Claims ### Claim 1 A medical device system configured to occlude an opening in a heart, the medical device system comprising: a delivery system including a handle and a catheter; and an implant removably coupled to the catheter, the implant including: a framework including a hub with frame segments extending radially from the hub; and a tissue growth member attached to the framework, the tissue growth member extending radially along the framework such that the tissue growth member extends to define an outer layer portion and an inner layer portion, the framework coupled to the inner layer portion, the tissue growth member extending with multiple voids defined therein, the tissue growth member including a filler material configured to temporarily fill the multiple voids of the tissue growth member. ### Claim 2 (depends on 1) The medical device system of claim 1, wherein the filler material is configured to fill the multiple voids defined along an outer surface of the outer layer portion. ### Claim 3 (depends on 2) The medical device system of claim 2, wherein the filler material is configured to fill the multiple voids defined in portions below the outer surface of the outer layer portion. ### Claim 4 (depends on 1) The medical device system of claim 1, wherein the tissue growth member comprises etched holes defined in the tissue growth member, the etched holes extending through each of the outer layer portion and the inner layer portion, the etched holes of the tissue growth member receiving a second filler material. ### Claim 5 (depends on 1) The medical device system of claim 1, wherein the filler material comprises a bio-dissolvable material. ### Claim 6 (depends on 5) The medical device system of claim 5, wherein the bio-dissolvable material comprises a bio-absorbable material. ### Claim 7 (depends on 1) The medical device system of claim 1, wherein the outer layer portion comprises multiple ePTFE layers. ### Claim 8 (depends on 1) The medical device system of claim 1, wherein the tissue growth member comprises a polyurethane material. ### Claim 9 (depends on 1) The medical device system of claim 1, wherein the inner layer portion comprises a laminated polymeric material, the laminated polymeric material configured to attach to the framework of the implant. ### Claim 10 A medical device configured to be percutaneously delivered to a heart with a catheter of a medical device delivery system, the medical device comprising: a framework including a hub with frame segments extending radially from the hub; and a tissue growth member attached to the framework, the tissue growth member extending radially along the framework such that the tissue growth member extends to define an outer surface and an inner surface, the framework coupled to the inner surface of the tissue growth member, the tissue growth member extending with multiple voids defined therein, the tissue growth member including a filler material configured to temporarily fill the multiple voids of the tissue growth member. ### Claim 11 (depends on 10) The medical device of claim 10, wherein the filler material is configured to fill the multiple voids defined along the outer surface of the tissue growth member. ### Claim 12 (depends on 11) The medical device of claim 11, wherein the filler material is configured to fill the multiple voids defined in portions below the outer surface of the tissue growth member. ### Claim 13 (depends on 10) The medical device of claim 10, wherein the tissue growth member comprises formed holes defined in the tissue growth member, the formed holes extending through each of the outer surface and the inner surface of the tissue growth member, the formed holes of the tissue growth member configured to receive a second filler material. ### Claim 14 (depends on 10) The medical device system of claim 10, wherein the filler material comprises a bio-dissolvable material. ### Claim 15 A method for occluding an opening in a heart, the method comprising: providing a medical device system extending to define a delivery system and an implant, the delivery system including a handle and a catheter, the catheter being removably coupled to the implant, the implant extending to define a framework, the framework including a hub with frame segments extending radially from the hub, the framework being attached to a tissue growth member, the tissue growth member extending radially along the framework to define an outer layer portion and an inner layer portion, the framework coupled to the inner layer portion, the tissue growth member extending to define multiple voids therein, the tissue growth member including a filler material configured to temporarily fill the multiple voids of the tissue growth member; and positioning the implant within a left atrial appendage of the heart. ### Claim 16 (depends on 15) The method according to claim 15, wherein the providing comprises providing the tissue growth member with etched portions extending through each of the outer layer portion and the inner layer portion of the tissue growth member. ### Claim 17 (depends on 16) The method according to claim 16, wherein the providing comprises providing the etched portions with a second filler material. ### Claim 18 (depends on 15) The method according to claim 15, wherein the providing comprises providing the tissue growth member with at least one of a polyurethane material and an ePTFE material.