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US 2024/0192246 A1Published application
System and method for determining dispensing volume for a liquid handler
AssigneeSpaero Inc.
InventorsDimitris Papageorgiou, Mitchell Adler
Life of this patent
Estimating the term…
Abstract
In variants, the method for determining dispensing volume for a liquid handler 110 can include: dispensing a droplet using the liquid hander 110, sampling a set of measurements of the droplet, determining the droplet volume based on the set of measurements, and/or any other suitable steps. In variants, the system 100 can include: the liquid handler 110, a droplet vessel 130, a measurement system 150, and/or any other suitable components.
Claims20
A method, comprising:
- using a liquid handling robot, dispensing a droplet from a pipette tip based on a set of liquid handling parameters for the liquid handling robot;
- sampling a set of images of the droplet;
- selecting a subset of images from the set of images, the subset of images comprising images sampled after the droplet has separated from the pipette tip;
- determining an estimated volume of the droplet based on the subset of images;
- and
- adjusting the set of liquid handling parameters based on the estimated volume.
3 more elements
A system, comprising:
- a vessel holding a first liquid, wherein a liquid handling robot is configured to dispense a droplet of a second liquid into the first liquid according to a set of liquid handling parameters.
- a camera configured to sample a set of images of the droplet;
- and
- a computing system configured to:
- detect the droplet in the set of images using a first model, wherein the first model distinguishes between air droplets and liquid droplets;
- and
- determine an estimated volume of the droplet based on the set of images using a second model.
4 more elements
Dependencies are inferred from the claim text.