Methods and systems for optimal capture of a multi-channel image from an lspr spectrometer
AssigneeNicoya Lifesciences Inc.
InventorSanat GANU
Life of this patent
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Abstract
Methods and systems for optimal capture of a multi-channel image in a LSPR spectrometry is described herein. The method comprises 1) finding a plurality of valid groupings of channels, 2) determining total capture times for each valid grouping of channels, 3) determining a measure of exposure sub-optimality, 4) estimating the expected error in peak wavelength for each valid grouping, 5) finding an optimal grouping of channels by identifying the grouping with the lowest estimate of expected error in peak wavelength and 6) capturing a subsequent multi-channel image using the optimal grouping.
Claims20
A method for optimal capture of a multi-channel image in a Localized Surface Plasmon Resonance (LSPR) spectrometer system, the method comprising:
- (a) finding a plurality of valid groupings of channels;
- (b) determining total capture times for each valid grouping of the plurality of valid groups of channels;
- (c) determining a measure of exposure sub-optimality;
- (d) estimating the expected error in peak wavelength for each valid grouping;
- (e) finding an optimal grouping of the plurality of valid groups of channels by identifying a valid grouping of the plurality of valid groups of channels with the lowest estimate of the expected error in peak wavelength;
- and
- (f) capturing a subsequent multi-channel image using the optimal grouping.
A method for optimal capture of a multi-channel image in an LSPR spectrometer system, the method comprising:
- (a) providing an LSPR spectrometer system comprising an illumination source, an LSPR sensor comprising multiple reaction channels, an imaging sensor and a processor;
- (b) exposing the multiple reaction channels to light from the illumination source;
- (c) capturing an image using the imaging sensor;
- and
- (d) using the processor to:
- 1) find a plurality of valid groupings of reaction channels,
- 2) determine total frame capture times for each valid grouping of the valid groupings of reaction channels,
- 3) find a measure of exposure sub-optimality and estimate expected error in peak wavelength for each valid grouping,
- 4) find an optimal grouping by finding a valid grouping of each valid grouping that has the lowest estimate of expected error in peak wavelength;
- and
- 5) capture a subsequent multi-channel image using the optimal grouping.
Dependencies are inferred from the claim text.