Vaccine for immunocompromised hosts
AssigneeUniversidade do Porto—Reitoria
InventorsPaula Maria DAS NEVES FERREIRA DA SILVA, Pedro Jorge Fonseca MADUREIRA
Life of this patent
Estimating the term…
Abstract
The invention provides peptides derived from a ubiquitous protein, and nucleic acids encoding such peptides. The invention extends to various uses of these peptides and nucleic acids, for example, as antigens for use in vaccines per se and in the generation of antibodies for use in therapeutic drugs for the prevention, amelioration or treatment of infections caused by sepsis-inducing bacteria. The invention particularly benefits immunocompromised hosts such as neonates, babies, children, women of fertile age, pregnant women, foetuses, the elderly and diabetics.
Claims18
A method of preventing an infection by sepsis-inducing bacteria, the method comprising administering, to a subject in need of such treatment, a peptide that has at least 90% amino acid sequence identity with a peptide found within GAPDH of one or more sepsis-inducing bacteria, or a functional fragment or functional variant thereof.
Dependencies are inferred from the claim text.