Anti-cea and anti-cd137 multispecific antibodies and methods of use
AssigneeBeiGene Switzerland GmbH
InventorsLiang QU, Tong ZHANG, Zhuo LI, Xin CHEN, Lin ZHU, Penghao WANG, Xiaosui Zhou, Yuanyuan XIE, Jie LI, Jian SUN, Jing SONG, Xuehui LI
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Abstract
Multispecific antibodies and antigen-binding fragments thereof that bind to human CEA and CD137, a pharmaceutical composition comprising said antibody, and use of the multispecific antibody or the composition for treating.
Claims31
A multispecific antibody or antigen-binding fragment thereof, comprising a first antigen binding domain that specifically binds to human CEA at amino acids 596 to 674 of SEQ ID NO:88 and a second antigen binding domain that specifically binds to human CD137.
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Dependencies are inferred from the claim text.