Compositions and methods for immunomodulatory bifunctional fusion molecules
OwnerChao SHIinventor
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Abstract
The disclosure is directed to a bispecific protein, comprising a first binding domain (BD1) that binds to a first target and a second binding domain (BD2) that binds to a second target, wherein the BD1 binds to IL6R or CD40, and BD2 binds to CD80/CD86; a composition comprising the bispecific protein, nucleic acids, cells, or any methods of use thereof.
Claims30
A bispecific protein, comprising a first binding domain (BD1) that binds to a first target and a second binding domain (BD2) that binds to a second target (i) wherein the BD1 binds to IL6R, and BD2 binds to CD80/CD86;
- or (ii) wherein the BD1 binds to CD40 and BD2 binds to CD80/CD86.
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Dependencies are inferred from the claim text.