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US 2024/0190977 A1Published application
IL-1 Receptor Accessory Protein Inhibitors and Uses Thereof
AssigneeLeo Pharma A/S
InventorsBirgitte Ursø, Waseem Sajid, Paola Lovato, Heidi Westh Bagger, Christoph Erkel, Petra Nussbaumer, Simon Schuster
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Abstract
The present disclosure provides novel antibodies and fragments thereof targeting IL-1RAcP (Interleukin-1 receptor accessory protein). Use of IL-1RAcP inhibitors are also provided herein.
Claims10
An antibody or antigen-binding fragment thereof that binds specifically to IL-1RAcP, wherein the antibody or antigen-binding fragment comprises an HCDR1 comprising the amino acid sequence of SEQ ID NO:
- 12, an HCDR2 comprising the amino acid sequence of SEQ ID NO:
- 13, an HCDR3 comprising the amino acid sequence of SEQ ID NO:
- 14, an LCDR1 comprising the amino acid sequence of SEQ ID NO:
- 9, an LCDR2 comprising the amino acid sequence of SEQ ID NO:
- 10, and an LCDR3 comprising the amino acid sequence of SEQ ID NO:
- 11.
3 more elements
Dependencies are inferred from the claim text.