Compositions and methods of treating pathogenic infections by using fusion proteins

Abstract

The present inventive concept provides a therapeutic platform that will prevent disease and reverse disease morbidity and mortality wherein the causative agent is a member of a broad class of infectious disease agents that mediate pathogenesis via mechanisms that are ameliorated by an interferon. The platform is based on the construction of single-chain soluble fusion proteins including a pathogen recognition domain, a linker and a pathogenesis-inhibiting effector domain.

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