Broad spectrum metalloproteinase inhibitor for the treatment of snakebite
OwnerSean B. Carroll, Fiona P. Ukkeninventors
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Abstract
Provided are compositions and methods for treatment of snakebites. The compositions include a metalloproteinase inhibitor. The compositions can further include one or more antibodies or antigen fragments thereof that bind to components of snake venom. The compositions are administered to an individual who has been envonmated by a snake to thereby reduce damage caused by the envonmation.
Claims13
A method comprising administering to an individual who has experienced envenomation by a snake a composition comprising a protein that has an amino acid sequence that is at least 95% identical to SEQ ID NO:1 such that development of injury to the individual from the envenomation is inhibited.
A composition comprising a combination of a protein that has an amino acid sequence that is at least 95% identical to SEQ ID NO:1 and at least one additional anti-venom agent.
A kit comprising an isolated or recombinantly produced protein that has an amino acid sequence that is at least 95% identical to SEQ ID NO:1 and a sealed container comprising said protein, the kit optionally including printed materials instructing a user to administer the composition to an individual who has experienced a snake bite, the kit further optionally comprising a syringe.
Dependencies are inferred from the claim text.