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US 2024/0190916 A1Published application
Novel peptide
AssigneeHysensbio
InventorsJoo Hwang PARK, Dong Seol Lee, Ji Hyun Lee
Life of this patent
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Abstract
A novel peptide, a polynucleotide encoding the peptide, an expression vector including the polynucleotide, and a pharmaceutical composition, quasi-drug composition, or health functional food composition including the peptide are disclosed. Uses of the peptide, polynucleotide, expression vector, and compositions are also disclosed.
Claims18
A peptide for promoting regeneration of a hard tissue or a dental pulp tissue and treating a dentin-dental pulp disease or a periodontal disease, wherein the peptide consists of any one of amino acid sequences of SEQ ID NOs:
- 1 to 64.
A method selected from the group consisting of:
- (a) a method for preventing or treating a dentin-dental pulp disease in a subject,
- (b) a method for preventing or treating a periodontal disease in a subject,
- (c) a method for promoting regeneration of a hard tissue or a dental pulp tissue in a subject, and
- (d) a combination thereof,
- said method comprising administering an effective amount of a composition comprising (i) a peptide consists of any one of the amino acid sequences of SEQ ID NOs:
- 1 to 64 and/or (ii) the peptide with a modification, said modification being selected from the group consisting of N-terminal or C-terminal acetylation, amidation or methylation;
- introduction of D-amino acid;
- peptide bond modification such as CH2—NH, CH2—S, CH2—S—O, or CH2—CH2;
- backbone modification;
- and side chain modification.
7 more elements
Dependencies are inferred from the claim text.