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US 2024/0190912 A1Published application
Separation media and purification methods for carbohydrate containing molecules using the same
AssigneeDonaldson Company, Inc.
InventorsJinxiang Zhou, Graham Temples, Daniel Henn
Life of this patent
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Abstract
Separation media includes a support substrate and a plurality of separation ligands immobilized on the support substrate. The plurality of separation ligands include an affinity group capable of binding to a carbohydrate. Methods of making the separation media and methods of using the separation media are disclosed.
Claims21
-39. (canceled)
A separation media comprising:
- a support substrate;
- and
- a plurality of separation ligands for formula SL1 or SL2
- wherein:
- Z is a separation group comprising an affinity group, the affinity group comprising a carbohydrate binding domain, a carbohydrate binging ligand, or both;
- and
- Rp1, Rp3, and Rp4 each independently comprise the reaction product of any one of RpA, RpB, RpC, RpD, RpE, RpF, RpG, RpH, RpI, RpJ, RpK, RpL, RpM or an isomer thereof,
- wherein RpA, RpB, RpC, RpD, RpE, RpF, RpG, RpH, RpI, RpJ, RpK, RpL, and RpM are represented by:
- wherein:
- U0, U1, U2, U3, U4, U5, U6, U7, U8 and U9 are each independently NH, O, or S;
- R is an organic group, H, or halogen;
- and
- Sp is a spacer comprising a divalent organic group.
10 more elements
The method of claim 58, wherein the method further comprises washing the separation media with a washing solution.
Dependencies are inferred from the claim text.