Melanocortin-4 receptor agonist
AssigneeLG Chem, Ltd.
InventorsEun Sil CHOI, Hee Dong PARK, Seung Wan KANG, Hye Won AHN, Deok Seong PARK
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Abstract
The present invention relates to a compound showing an excellent agonistic activity for a melanocortin receptor and, more specifically, to the compound of chemical formula 1, a pharmaceutical composition containing same as an active ingredient, and a use thereof. In detail, the compound of the present invention exhibits an excellent agonistic activity for melanocortin-4 receptor and thus, can be advantageously used especially for preventing or treating obesity, diabetes, inflammation, and impotence.
Claims14
A compound of the following Formula 1, or a pharmaceutically acceptable salt or isomer thereof:
- wherein
- R1 is C2-C5 alkyl;
- R2 is halo;
- R3 is hydrogen or halo;
- R4 is C1-C3 alkyl;
- and
- n is an integer of 1 or 2;
- provided that n is 2, when R2 is chloride and R3 is hydrogen.
Dependencies are inferred from the claim text.