# US 2024/0189591 A1 · Treatment system using vagus nerve stimulation and operating method thereof > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 2024/0189591 A1 - Document ID: US20240189591A1 - Status: Published application - Kind: A1 - Application number: 17/792,570 - Filed: 2021-12-16 - Published: 2024-06-13 - Earliest claimed: 2021-12-16 - Assignees: Korea University Research and Business Foundation - Applicants: Korea University Research and Business Foundation - Inventors: Jae Jun SONG; Hyuk CHOI; Guk Han KIM; Yong Ho JUNG - Web page: https://patentgrep.com/patent/US20240189591A1 ## CPC - A61N 1/36031: {using physiological parameters for adjustment} - A61B 5/024: Measuring pulse rate or heart rate - A61B 5/16: Devices for psychotechnics (using teaching or educational appliances G09B1/00 - G09B7/00); Testing reaction times {; Devices for evaluating the psychological state} - A61B 5/372: Analysis of electroencephalograms - A61M 21/00: Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis - A61M 21/02: for inducing sleep or relaxation, e.g. by direct nerve stimulation, hypnosis, analgesia (for massage A61H; electrotherapy A61N, e.g. applying alternating or intermittent electric currents for producing anaesthesia A61N1/36021) - A61N 1/0456: {Specially adapted for transcutaneous electrical nerve stimulation [TENS]} - A61N 1/0472: {Structure-related aspects} - A61N 1/36: for stimulation - A61N 1/36034: {specified by the stimulation parameters} - A61N 1/36036: {of the outer, middle or inner ear} - A61N: ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY (measurement of bioelectric currents A61B; surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body A61B18/00; anaesthetic apparatus in general A61M; incandescent lamps H01K; infrared radiators for heating H05B) - A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D) - A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)} ## Abstract Proposed is a treatment system using vagus nerve stimulation. The treatment system includes a treatment part including an electrode configured to be worn on at least one of the left and right ears and configured to generate electrical stimulation on the vagus nerve in the auricle, a controller configured to transmit an electrical stimulation signal for generating the electrical stimulation to the treatment part, an input part configured to allow a user to input user information, and a measurement part configured to measure biometric information on the user. The controller adjusts an intensity and a pattern of the electrical stimulation on the basis of the biometric information measured by the measurement part, and adjusts a treatment protocol including treatment time and treatment intensity on the basis of the biometric information measured by the measurement part and the user information input by the input part. ## Claims ### Claim 1 A treatment system using vagus nerve stimulation, the treatment system comprising: a treatment part including an electrode configured to be worn on at least one of the left and right ears and configured to generate electrical stimulation on the vagus nerve in the auricle; a controller configured to transmit an electrical stimulation signal for generating the electrical stimulation to the treatment part; an input part configured to allow a user to input user information; and a measurement part configured to measure biometric information on the user, wherein the controller adjusts an intensity and a pattern of the electrical stimulation on the basis of the biometric information measured by the measurement part, and adjusts a treatment protocol including treatment time and treatment intensity on the basis of the biometric information measured by the measurement part and the user information input by the input part. ### Claim 2 (depends on 1) The treatment system of claim 1, wherein the measurement part measures brainwaves of the user, and the controller adjusts the intensity and pattern of the electrical stimulation on the basis of the measured brainwaves. ### Claim 3 (depends on 2) The treatment system of claim 2, wherein the controller performs fast Fourier transform (FFT) analysis on the brainwaves, and adjusts the electrical stimulation on the basis of an amount of change in the brainwaves obtained by comparing a composition ratio of the brainwaves. ### Claim 4 (depends on 1) The treatment system of claim 1, wherein the measurement part measures a heart rate of the user, and the controller adjusts the intensity and pattern of the electrical stimulation on the basis of the measured heart rate. ### Claim 5 (depends on 4) The treatment system of claim 4, wherein the controller adjusts the intensity of the electrical stimulation by comparing heart rate variability with a reference value. ### Claim 6 (depends on 1) The treatment system of claim 1, wherein the user information includes disease information related to a disease and other general information, the disease information includes first disease information on an intensity and a frequency of symptoms input while the electrical stimulation is applied and second disease information as other disease-related information, and the controller adjusts the treatment protocol on the basis of the first disease information. ### Claim 7 (depends on 6) The treatment system of claim 6, wherein a treatment process is composed of a plurality of sessions, and the treatment protocol of a subsequent session is adjusted on the basis of the first disease information input by the user in a previous session. ### Claim 8 (depends on 1) The treatment system of claim 1, wherein the treatment part further includes an acoustic device configured to generate a sound, and the controller transmits a sound signal to the acoustic device, and the controller derives a hearing loss pattern and a hearing loss frequency on the basis of the information input by the user in a state in which a sound is applied, and adjusts an attenuation frequency and a width of a bandpass filter for treatment of hearing loss. ### Claim 9 (depends on 1) The treatment system of claim 1, further comprising an environment measurement part configured to measure surrounding environment information, wherein the controller adjusts the treatment protocol by converting the surrounding environment information measured by the environment measurement part into a stress index. ### Claim 10 (depends on 9) The treatment system of claim 9, wherein the environment measurement part is installed in a wearable device. ### Claim 11 (depends on 1) The treatment system of claim 1, wherein the measurement part is installed in the treatment part worn on the user's ear. ### Claim 12 (depends on 1) The treatment system of claim 1, wherein the measurement part is installed in a wearable device. ### Claim 13 A method of operating a treatment system using vagus nerve stimulation, the method comprising: an information collecting step of inputting by a user, user information on an intensity and a frequency of symptoms in a state in which stimulation for diagnosis is applied to the user's body through an electrode that is configured to be worn on at least one of the left and right ears and configured to generate electrical stimulation, and then measuring biometric information of the user; a treatment program designing step of determining an intensity and a pattern of the electrical stimulation on the basis of the measured biometric information and determining a treatment protocol including treatment time and treatment intensity on the basis of the biometric information measured by a measurement part and the user information input by an input part, and; a treatment step of stimulating the vagus nerve by applying a designed treatment program to the electrode. ### Claim 14 A treatment system using vagus nerve stimulation, the treatment system comprising: a treatment part including an electrode configured to be worn on at least one of the left and right ears and configured to generate electrical stimulation on the vagus nerve in the auricle; a controller configured to transmit an electrical stimulation signal for generating the electrical stimulation to the treatment part; an input part configured to allow a user to input user information; a measurement part configured to measure biometric information on the user; and a server configured to send and receive data to and from the controller, wherein the server adjusts an intensity and a pattern of the electrical stimulation on the basis of the biometric information measured by the measurement part, and adjusts a treatment protocol including treatment time and treatment intensity on the basis of the biometric information measured by the measurement part and the user information input by the input part to transmit the adjusted treatment protocol to the controller. ### Claim 15 (depends on 14) The treatment system of claim 14, wherein the server adjusts the intensity, the pattern, and the treatment protocol of the electrical stimulation through an artificial intelligence (AI)-based algorithm. ### Claim 16 (depends on 14) The treatment system of claim 14, wherein the server provides a diagnosis stimulation protocol and a treatment stimulation protocol. ### Claim 17 (depends on 14) The treatment system of claim 14, wherein the server provides video and sound content for diagnosis and video and sound content for treatment. ### Claim 18 (depends on 14) The treatment system of claim 14, wherein the server provides video and sound content for training. ### Claim 19 (depends on 14) The treatment system of claim 14, wherein the server is connected to a medical terminal used by an expert and adjusts the intensity, the pattern, and the treatment protocol of the electrical stimulation through the medical terminal. ### Claim 20 (depends on 19) The treatment system of claim 19, wherein the medical terminal displays personal information and disease-related information of the user.