Deoxyribonucleoside or deoxyribonucleotide having novel artificial base applicable to screening for dna aptamer, and nucleic acid containing the same

Abstract

An object of the present application is to overcome problems in obtaining DNA aptamers in conventional methods, including the lack of diversification of interactions with target molecules, the increase in the cost for obtaining aptamers by post modification, and the limitation of target molecule species because of electric charges, and to provide a technique for obtaining highly active aptamers as inexpensively as possible. Provided is a nucleoside or nucleotide having, as a base, a structure of formula I. In formula I, R1 is a substituted C1-C3 alkyl group, a substituted or unsubstituted C4-C9 alkyl group, a substituted or unsubstituted aryl group, a substituted or unsubstituted cycloalkyl group, a substituted or unsubstituted aralkyl group, or a substituted or unsubstituted heteroaryl group.

Dependencies are inferred from the claim text.