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US 2024/0182880 A1Published application
Protease variants and uses thereof
AssigneeDanisco US Inc.
InventorsRichard R. Bott, David A. Estell, Frits Goedegebuur, Harm Mulder, Sina Pricelius
Life of this patent
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Abstract
Disclosed herein is one or more subtilisin variants, nucleic acids encoding same, and compositions and methods related to the production and uses thereof, including one or more subtilisin variants that has improved stability and/or soil removal compared to one or more reference subtilisin.
Claims11
1-36. (canceled)
A subtilisin variant comprising an amino acid sequence with at least 95% amino acid sequence identity to the amino acid sequence of SEQ ID NO:
- 6, comprising the amino acid substitution S101R in combination with S130A, wherein the amino acid positions of the variant are numbered by correspondence with the amino acid sequence of SEQ ID NO:
- 26, and wherein the variant has an improved property when compared to a reference subtilisin comprising the amino acid sequence of SEQ ID NO:6, wherein the improved property is selected from the group consisting of improved cleaning performance in detergent and improved productivity.
Dependencies are inferred from the claim text.