Mutant mad7 protein
AssigneeSetsurotech Inc.
InventorsShunya HOZUMI, Koichi NISHIMURA, Okura MASUDA, Satoru TAKADERA, Risa KAINUMA, Yukiko YAMASHITA, Shun SAWATSUBASHI
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Abstract
A mutant MAD7 protein with higher target-site cleavage activity is provided. The mutant MAD7 protein includes an amino acid sequence B obtained by introducing mutations into an amino acid sequence A represented by SEQ ID NO:1, the amino acid sequence B including amino-acid substitution mutations of K169 and D529 in the amino acid sequence A.
Claims24
A mutant MAD7 protein comprising an amino acid sequence B, the mutant MAD7 protein having mutations in an amino acid sequence A represented by SEQ ID No. 1, the amino acid sequence B comprising amino-acid substitution mutations of K169 and D529 in the amino acid sequence A.
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