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US 2024/0182525 A1Published application
Novel bicyclic compound, optical isomer thereof or pharmaceutically acceptable salt thereof, use thereof, and preparation method therefor
AssigneeKorearesearch Institute of Bioscience and Biotechnology
InventorsJong Seog AHN, Jun Pil JANG, Jae-Hyuk JANG, Sung-Kyun KO, Min Cheol KWON, Gui Ja HWANG, Jae-Won LEE
Life of this patent
Estimating the term…
Abstract
The present invention provides a compound represented by chemical formula 1, an optical isomer thereof or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition for preventing or treating Wnt/β-catenin signaling-associated diseases, comprising same.
Claims20
A compound represented by the following Chemical Formula 1, an optical isomer thereof, or a pharmaceutically acceptable salt thereof:
- in Chemical Formula 1 above,
- R1, R2, R3, R4, R5 and R6 are the same as or different from each other, and are each independently a hydrogen atom or hydroxyl (—OH);
- R7 is a substituted or unsubstituted C1-6 alkyl, a substituted or unsubstituted C2-6 alkene, a substituted or unsubstituted C3-8 heterocycloalkyl containing at least one oxygen atom (O) as a heteroatom, or a substituted or unsubstituted C3-8 heterocycloalkene containing at least one oxygen atom (O) as a heteroatom (wherein at least one H of the substituted C1-6 alkyl, the substituted C2-6 alkene, the substituted C3-8 heterocycloalkyl, or the substituted C3-8 heterocycloalkene may each independently be substituted with hydroxyl (—OH), a halogen atom, C1-6 alkyl or oxo (═O));
- n is an integer of either 0 or 1;
- 10 when n is 0, X1 and X2 are the same as or different from each other, and are each independently a hydrogen atom or hydroxyl (—OH);
- and
- when n is 1, X1 and X2 are each independently a single bond, and X3 is —O—.
4 more elements
Streptomyces rapamycinicus KTCT 14890BP.
Dependencies are inferred from the claim text.