Oral vaccine composition
AssigneesKaico Ltd., Kagoshima University, Kyushu University, National University Corporation
InventorsKenta YAMATO, Takeshi MIYATA, Takahiro KUSAKABE, Jae Man LEE, Akitsu MASUDA
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Abstract
A method of easily producing an immunogenic pupa for oral administration and a pupa for oral administration produced by the method are provided. The method is a method of producing a pupa for oral administration, including a step of infecting a larva or pupa of an insect capable of being baculovirus-infected with a recombinant baculovirus having DNA encoding an antigen protein introduced therein and freeze-drying a pupa having pupated from the infected larva or the infected pupa.
Claims19
A pupa of an insect capable of being baculovirus-infected, which is infected with a recombinant baculovirus having DNA encoding an antigen protein introduced therein and then freeze-dried.
A cell capable of being baculovirus-infected, which is infected with a recombinant baculovirus having DNA encoding an antigen protein introduced therein and then freeze-dried.
A method of producing a pupa for oral administration, comprising a step of infecting a larva or pupa of an insect capable of being baculovirus-infected with a recombinant baculovirus having DNA encoding an antigen protein introduced therein and freeze-drying a pupa having pupated from the infected larva or the infected pupa.
A method of producing a cell for oral administration, comprising a step of infecting a cell capable of being baculovirus-infected with a recombinant baculovirus having DNA encoding an antigen protein introduced therein and freeze-drying the infected cell.
A method of producing an oral vaccine, comprising a step of infecting a larva or pupa of an insect capable of being baculovirus-infected with a recombinant baculovirus having DNA encoding an antigen protein introduced therein and freeze-drying a pupa having pupated from the infected larva or the infected pupa.
A method of producing an oral vaccine, comprising a step of infecting a cell capable of being baculovirus-infected with a recombinant baculovirus having DNA encoding an antigen protein introduced therein and freeze-drying the infected cell.
Dependencies are inferred from the claim text.