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AssigneePfizer Inc.
InventorsCatherine Alex, Annaliesa Sybil Anderson, Bishwa Raj Bhetuwal, Zecheng Chen, Kaushik Dutta, Caitlyn Gallagher, Jianxin Gu, Isis Kanevsky, Jin-Hwan Kim, Justin Keith Moran, Suddham Singh, Naveen Surendran, Abhishek Ravindra Vartak, YuYing Yang
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The present invention relates to new immunogenic compositions comprising conjugated Streptococcus pneumoniae capsular saccharide antigens (glycoconjugates) and uses thereof. Immunogenic compositions of the present invention will typically comprise at least one glycoconjugate from a S. pneumoniae serotype not found in Prevnar, Synflorix and/or Prevnar 13. The invention also relates to vaccination of human subjects, in particular infants and elderly, against pneumoccocal infections using said novel immunogenic compositions.
An immunogenic composition comprising glycoconjugates from S. pneumoniae serotypes 1, 3, 4, 5, 6A, 6B, 7F, 8, 9V, 10A, 11A, 12F, 14, 15B, 18C, 19A, 19F, 22F, 23F and 33F and additionally comprises from 1 to 5 glycoconjugates from S. pneumoniae serotypes 15A, 23A, 23B, 24F and/or 35B.
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