Compositions and methods for treating and preventing gastrointestinal inflammation
AssigneeDupont Nutrition Biosciences Aps
InventorsPatrick Boyaval, Sebastien Guery, Mathias Richard
Life of this patent
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Abstract
Provided herein are compositions containing fungus, e.g., yeast, useful for treating and/or preventing gastrointestinal inflammation, and/or diseases, disorders, or conditions associated therewith, in a subject in need thereof and methods for using the same.
Claims18
(canceled)
The method of claim 12, wherein the Cyberlindnera jadinii is the strain deposited at DSMZ [Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH, Inhoffenstrasse 7B, D-38124 Braunschweig—Germany] under number DSM 33763 or a strain having all of the identifying characteristics of the Cyberlindnera jadinii strain deposited at DSMZ under number DSM 33763.
The method of claim 12, wherein the Kluyveromyces lactis is the strain deposited at DSMZ [Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH, Inhoffenstrasse 7B, D-38124 Braunschweig—Germany] under number DSM 33764 or a strain having all of the identifying characteristics of the Kluyveromyces lactis strain deposited at DSMZ under number DSM 33764.
The method of claim 12, wherein the effective amount of the Cyberlindnera jadinii or the Kluyveromyces lactis in the composition is present at from about 1×109 CFU/g to about 5×1010 CFU/g of composition.
The method of claim 12, wherein the composition is a probiotic.
The method of claim 12, wherein the composition is a pharmaceutical composition and further comprises at least one pharmaceutically acceptable carrier and/or excipient.
The method of claim 12, wherein the composition is formulated for oral administration or topical administration.
The method of claim 12, wherein the composition is a food product, food ingredient, dietary supplement, or medicament.
The method of claim 12, wherein the disease, disorder, or condition is IBD, IBS, cancer, chemotherapy-induced gastrointestinal inflammation, radiation-induced gastrointestinal inflammation, immunotherapy-induced gastrointestinal inflammation, bacterial infection, viral infection, fungal infection, antibiotic use, aging, dysbiosis, obesity, type 2 diabetes, metabolic syndrome, asthma, atherosclerosis, non-alcoholic fatty liver disease, multiple sclerosis, or skin inflammation.
A tablet, chewable gum, capsule, granule, powder, sachet, patch, cream, or ointment comprising Cyberlindnera jadinii or Kluyveromyces lactis.
A kit comprising:
- (a) a composition comprising Cyberlindnera jadinii or Kluyveromyces lactis;
- and
- (b) written instructions for administration to a subject.
A method for treating and/or preventing gastrointestinal inflammation and/or a disease, disorder or condition associated with gastrointestinal inflammation, in a subject in need thereof, comprising administering a composition comprising an effective amount of Cyberlindnera jadinii or Kluyveromyces lactis to the subject.
(canceled)
Dependencies are inferred from the claim text.